Survival Noninferiority

Survival Noninferiority is a program to calculate either estimates of sample size or power for noninferiority studies. Exponential distributions are assumed and are specified using the ratio of the hazard for the experimental treatment to the hazard for the standard treatment. The ratio of hazard rates describing noninferiority is defined in the same way.

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User Input
Program Output

Type of Calculation


Survival Statistic Input




Alpha (one-sided)
Competing Risk
Proportion in Experimental Sample
Accrual Period
Follow-up Period
Power
Sample Size
Noninferiority Margin (Hazard Ratio Between Standard and Experimental Arm (Under H0))
Hazard Rate in Standard Arm
Median Survival in Standard Arm
Survival Probability in Standard Arm
at Time
Hazard Ratio (Under Ha)


Power
Sample Size
Hazard Rate in Standard Arm
Hazard Rate in Experimental Arm (Under H0)
Hazard Rate in Experimental Arm (Under Ha)
Median Survival in Standard Arm
Median Survival in Experimental Arm (Under H0)
Median Survival in Experimental Arm (Under Ha)