Survival Interaction

Interaction Survival is a program to calculate either estimates of sample size or power for tests of interaction. Exponential distributions are assumed and are specified as a ratio of the hazard ratio for the treatment effect in stratum 1 to the hazard ratio for the treatment effect in stratum 2. The program allows for unequal sample size allocation in the four cells defined by the two treatment groups and two strata. An exponentially distributed competing risk is also permitted.

For further details, view the Help Document.


User Input
Program Output

Type of Calculation


Type of Test


Survival Statistic



Alpha
Accrual
Follow
Power
Sample Size
Comp Risk

Cell Freq Treat1/Strat1
Cell Freq Treat1/Strat2
Hazard Rate Treat1/Strat1
Hazard Rate Treat1/Strat2
Median Survival Treat1/Strat1
Median Survival Treat1/Strat2
Survival Probability Treat1/Strat1
Survival Probability Treat1/Strat2
at Time
Cell Freq Treat2/Strat1
Cell Freq Treat2/Strat2
Haz Ratio T1/T2 Strat1
Haz Ratio T1/T2 Strat2


Power
Sample Size
Hazard Rate Treat1/Strat1
Hazard Rate Treat1/Strat2
Median Survival Treat1/Strat1
Median Survival Treat1/Strat2